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McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, et al

10.1038/s41587-019-0209-9 8 CallahanB

Connelly et al

5.3 Suppression of IL-1 production by modulating the NLRP3 inflammasome One study revealed a negative correlation between CARS2 expression and the production of inflammatory cytokines, such as IL-1 (109)

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Nevertheless, the effect of ethanol consumption on the total hepatic GSH pool is equivocal in that studies have shown decreased, unchanged or increased levels 12,13,14 , most likely related to differences in ethanol exposure regimes and/or analytical assays