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After pre-treatment, cells were stimulated by addition of forskolin + IBMX (10 M each) + 10 mM glucose, or AngII (1 M) or CNO (10 M) for 10 min at 37 C

Nature 483 , 474478 (2012)

More recent work improving topical copper-peptide delivery demonstrated hair regrowth and Wnt/-catenin activation in mice a preclinical model, not people (Liu et al., 2023, DOI)

McIntyre RS, Powell AM, Kaidanovich-Beilin O, Soczynska JK, Alsuwaidan M, Woldeyohannes HO, Kim AS, Gallaugher LA (2013) The neuroprotective effects of GLP-1: possible treatments for cognitive deficits in individuals with mood disorders

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When paired with Emtones RF technology, exosomes amplify the treatments effect, leading to more pronounced skin tightening and cellulite reduction