In this double-blind, placebo-controlled phase 2, trial, 507 adults with obesity (body mass index 30 kg m 2 or 27 kg m 2 with at least one obesity-associated complication (excluding diabetes) were randomized to nine groups (1:1:1:1:1:1:1:1:1 ratio) to receive treatment for 48 weeks: placebo, bimagrumab (10 mg kg 1 or 30 mg kg 1 intravenously every 12 weeks), semaglutide (1.0 mg or 2.4 mg subcutaneously once a week) and combinations thereof
The transient nature of side effects is supported by median duration data showing nausea episodes lasting 8 days, diarrhea 3 days, and vomiting 2 days
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Ramirez RD, D'Atri S, Pagani E, Faraggiana T, Lacal PM, Taylor RS et al
The big question I get is, does ozempic work for weight loss or is it just another trend