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Fasting is required for rescuing hippocampal-dependent long-term memory in both sexes We examined the contribution of fasting on CR-induced improvements in cognition by performing behavioral assays on 12-month-old 3xTg and NTg mice that had been fed either an AL, DL, or CR diet prior to sacrificing them for the histological assays described above

Biomolecules 12 (11), 1702

First, inhibiting NRF2 activation, such as using Deubiquitinase 3 (DUB3) inhibitors, promotes NRF2 ubiquitination and degradation

A.Ndukwe ErlingssonU

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