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Dark urine whilst taking Ozempic (semaglutide) can arise from several mechanisms , though it is not directly listed as a common adverse effect in the product's Summary of Product Characteristics

It also plays the role of free radical scavenger by reducing the production of ROS (70)

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PlexusDx offers the Precision Peptide Genetic Test ($99 add-on after your first month of treatment), which maps 14 metabolic pathways and 49 peptides to reveal whether you carry genetic variants affecting vasodilation, inflammation response, and tissue repair

Human mutation data reported