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Interestingly, in the absence of ADH5, FA induces a significant accumulation of ROS at non-toxic FA concentrations, which is further exacerbated by blocking GSH synthesis (Fig

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Over the next five years, after accounting for patients' other health conditions, the hospitalization rate was 19% lower and the mortality rate was 15% lower in the group treated with bone-strengthening medications

GSTs were shown to catalyze the conjugation between various xenobiotics with electrophilic centers (Figure 1) and the nucleophilic GSH, thus tagging the xenobiotic for vacuolar sequestration (Martinoia et al., 1993)

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