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It's a nasty slippery slope

Early signs include tingling or 'pins and needles' in the feet and hands, numbness in the extremities, burning pain (often worse at night), balance problems, and muscle weakness

Combination therapy erases this gap while adding complexity and cost

It is often a fit for people whose hunger has defeated repeated diet attempts, for those whose progress on semaglutide or tirzepatide has plateaued, and for those with insulin resistance or prediabetes who benefit from steadier post-meal blood sugar

The results most people want (firmer-looking skin, fuller-looking hair) need the full 6-8 weeks

This typically affects people who are overweight or who have insulin resistance such as diabetes patients