Here are a few reasons this can happen
But the most widely agreed upon advice for muscle retention can be found in an influential paper published by the Academy of Nutrition and Dietetics, which recommends consuming between 1.2 to 1.5 grams of protein per kilogram of body weight
Results vary, and weight loss tends to be more gradual early on as appetite suppression builds and treatment progresses
Challenges in Research Despite the exciting possibilities, there are challenges in conducting this research: Limited Focus on Mental Health Most GLP-1 studies are focused on diabetes and weight management, so funding and attention for mood-related studies are currently limited
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Some lean tissue goes with any meaningful weight loss, the proportions on these drugs look similar to other methods, and the outcome is heavily influenced by what you do alongside the medication