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5 Through topical application of hydroquinone, there is reversible depigmentation of the skin via inhibition of tyrosinase which normally converts tyrosine to 3,4-dihydroxypheylalanine (dopa)

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Subclinical Hypothyroidism Elevated TSH levels characterize subclinical hypothyroidism, while free T4 remains within the normal range

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Oxidative stress arises when there is an imbalance between oxidant generation and antioxidant capacity, leading to the accumulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), ultimately resulting in cellular injury and dysfunction 1