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In the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER) study, patients with type 2 diabetes and high cardiovascular risk were randomized to receive a daily subcutaneous injection liraglutide or placebo

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Growth hormone secretagogues like sermorelin have shown modest improvements in body composition and lean muscle mass in aging populations, but head-to-head comparison trials with dual-peptide regimens are sparse in published literature

Efficacy and safety at 1mg have not been established in published trial data

Postolache L, Monier A, Lhoir S

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