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The most commonly reported adverse events in combination groups were nausea, vomiting, and constipation

2001 Jul 15;61(14):5378-81

The conservative approach involves cycling use (4-12 weeks on, 4-6 weeks off) to prevent potential receptor downregulation and maintain effectiveness

Treatment of aggressive prolactinoma with temozolomide: A case report and review of literature up to date

Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production

M.J.D has received grants from AstraZeneca, Novo Nordisk, Boehringer Ingelheim, Janssen and Sanofi-Aventis and Eli Lilly