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doi: 10.1016/j.biochi.2013.01.002

conducted target trial emulations comparing dual GLP-1/GIP agonists to GLP-1 monotherapy in patients with type 2 diabetes, finding that dual agonists were linked to numerically lower risks of MALOs, although confidence intervals overlapped, suggesting that extended observation period and larger patient cohorts may be needed to definitively establish comparative effectiveness [61]

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Serum dickkopf-1 (DKK1), osteoprotegerin (OPG), osteopontin (OPN), sclerostin (SOST), and fibroblast growth factor-23 (FGF-23) levels were determined using the MILLIPLEX Human Bone Magnetic Bead Panel (catalog number [cat