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Because of the mechanism of action of DPP-IV inhibitors, it is presumed that DPP-IV inhibitors contribute to GV reduction 27

Creatine may enhance glucose uptake in muscle by boosting phosphocreatine stores and facilitating more rapid ATP turnover during contractions, which can upregulate glucose transporter activity

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La interaccin se produce en diversos tejidos (pncreas, cerebro, miocardio, endotelio, rin, sistema digestivo), lo que motiva que sus acciones, entre las que cabe destacar el control glucmico con mnimo riesgo de hipoglucemia, posean carcter pleiotrpico (fig

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