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Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases

Vitamin B 6 (Pyridoxine) Deficiency Causes Caused by dietary malnutrition, alcoholism, pregnancy, certain metabolic diseases (eg, homocystinuria), or certain pharmacologic agents (isoniazid, penicillamine, oral contraceptives) that interfere with pyridoxine metabolism or act as competitive inhibitors at pyridoxinebinding sites

doi: 10.1186/1471-230X-9-6 19 ClarkeG.McKernanD

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How much you should get The FDA recommends adults and children over age 4 get 16 mg of niacin each day