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Protection against lethal sepsis following immunization with Candida species varies by isolate and inversely correlates with bone marrow tissue damage

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Advice to Patients Advise patients to read the medication guide and instructions for use prior to initiating therapy and each time prescription is refilled

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Medications know to cause bone marrow suppression (e.g., myelosuppressive antineoplastic agents) may result in a blunted or impeded response to methylcobalamin, vitamin B12 therapy