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Obese mice and rats treated with AOD9604 showed significant decreases in adipose tissue depot weights, reductions in adipocyte size observed histologically, and improvements in body composition measured by DEXA scanning or MRI

Studies indicate that HIF-2, upon stimulation by inflammatory factors such as IL-1, leads to a decrease in GSH levels, thereby increasing chondrocytes sensitivity to lipid peroxidation and ferroptosis

For HMOX1 and SRXN1, global cellular GFP intensity was detected as an indicator of their respective expression levels

Hypoglycemia Rare when used alone