Figure 3 Citrullination of arginine residues in myelin basic protein (MBP)and likely other CNS proteins as wellseems to be one important post-translational modification associated with inflammatory demyelination
Diabetic ketoacidosis rarely is associated with triggering destruction of G6PD-deficient red cells
In the pathophysiology of depression, IL-1 synergistically contributes to central 5-HT system hypofunction: it activates IDO1, diverting Trp metabolism away from 5-HT synthesis, and upregulates the SERT to accelerate the clearance of 5-HT from the synaptic cleft (Zhu et al., 2006)
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Generation of hydrogen peroxide by incidental metal ion-catalyzed autooxidation of glutathione
Cultures were incubated aerobically with vigorous shaking until they reached an OD 600 0.10.15
