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Gastroenterology 130 , 150164 (2006)

Patients should be encouraged to: Consume a balanced diet rich in calcium (dairy products, fortified plant-based alternatives, leafy greens) Ensure adequate protein intake to preserve lean muscle mass during weight loss Engage in regular physical activity following UK Chief Medical Officers' guidelines Limit alcohol consumption to no more than 14 units per week, spread over 3 or more days Avoid smoking, which impairs bone health Maintain safe home environments to reduce fall risk When to seek medical advice : Patients should contact their GP or diabetes specialist nurse if they experience unexplained bone pain, sustain a fracture from minimal trauma, or have concerns about their bone health

[1] Observational studies and case reports have documented acne flares temporally associated with B12 supplementation, particularly following high-dose intramuscular injections

Semaglutide, marketed under names like Ozempic and Rybelsus, is a GLP-1 receptor agonist designed to help manage type 2 diabetes

CVD indication only (not obesity): Kansas and Vermont

Dowd, Curtis Huttenhower, Matthieu Pichaud, Esra I