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The lowered absorption rate and increased frequency attributed to oral supplements can cause the overall treatment process to be slower than that of B12 injections

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While the study found no significant differences in the primary efficacy endpoint (time to first tolerated meal), the ipamorelin group showed reduced median time to first tolerated meal (25.3 hours versus 32.6 hours in placebo) and had fewer overall treatment-emergent adverse events (87.5% versus 94.8%)

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International Association of Fish Meal Manufacturers