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Animal studies using euglycemic clamp techniques, the gold standard for insulin sensitivity assessment, confirmed that chronic AOD-9604 treatment produced no adverse effects on insulin sensitivity

All analyses were performed in R software (version 4.3.3)

However, GLP-1 has a very short half-life [5]

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Therapy should also be considered in those with a compelling need to minimise weight gain or lose weight, because the links between diabetes and obesity are well known

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