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Having objective data on key hormonal markers before, during, and after a research protocol is the gold standard for understanding a compound's true physiological impact

Stress Multiple epidemiological studies have implicated that stress, both psychosocial and/or physical, is a trigger of onset or exacerbation of abdominal pain and bowel dysfunction, particularly in IBS-C [76, 77]

It is always a good idea to mention this to your healthcare provider so they can monitor your progress

doi: 10.1210/jc.2011-3350 28 BaroniMGGiorginoFPezzinoVScaroniCAvogaroA