She is very knowledgeable, especially when it comes to hormones
Diabetologia 59:10591069 Nowak C, Lind M, Sumnik Z, Pelikanova T, Nattero-Chavez L, Lundberg E et al (2022) Intralymphatic GAD-Alum (Diamyd) improves glycemic control in Type 1 diabetes with HLA DR3-DQ2
It says research combining fasting with GLP-1 medications remains limited, and that most clinical data covers weight loss and glycemic control under standard treatment rather than the safety of extended fasting periods
A separate Phase 2 trial in people with type 2 diabetes was also published in the NEJM in 2023, reporting meaningful reductions in HbA1c alongside weight loss
The receptor DNA binding domain requires a CTE of minimally four residues (amino acids 626 TLGA 629) for proper binding to an ARE (androgen response element) with an inverted repeat of high affinity ARE-half sites and a CTE of at least twelve residues (amino acids 626 TLGARKLKKLGN 637) for binding to an ARE with one high and one low affinity half site (125)
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