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Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease

These results suggest that the increased expression of GSTO2 could be the result of reduced BDNF transport in striatal tissue by mHTT followed by increased TH in the SNcVTA and subsequent striatal hyperdopaminergia (Fig

In addition, the cognitive abilities of persons afflicted with certain genetic predispositions to cognitive dysfunction may also be increased, e.g

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For hygiene purposes, the inhalation cannula should be replaced after 20 uses or sooner if noticeable dirt or wear occurs