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This strategy could enhance the efficacy of immunotherapies by increasing tumor immunogenicity, thereby improving responsiveness to treatments such as immune checkpoint inhibitors and macrophage-targeted therapies, including CSF1R and TREM2 inhibitors

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Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

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In reports up to 158 pages long, the agency detailed the science behind the immune response risk in synthetic peptides, listed documented adverse events associated with the drugs and summarized the limited research on human subjects

BMJ 321 , 789792 (2000)