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Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2

The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)

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Au cours de chaque campagne, entre 20 et 40 patients ont pu bnfici de l'expertise de Christophe, principalement dans le domaine de la pathologie prostatique

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