In HBV and HCV, persistent mitochondrial stress drives hepatocyte apoptosis, fibrosis, and hepatocarcinogenesis (Kim et al., 2014
The condition ranges in severity from asymptomatic elevation of CK levels to severe, life-threatening cases associated with markedly elevated CK, myoglobinuria, acute renal failure, compartment syndrome and disseminated intravascular coagulation [3]
The stakes are high: More than 40% of U.S
For safety, all participants were followed for 6 weeks after the last dose was administered
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Marconi, D