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Semaglutide is an FDA-approved GLP-1 receptor agonist designed for chronic weight management in adults with obesity, or those overweight with at least one weight-related condition

While this was a specific clinical population and the findings are hypothesis-generating rather than definitive, it suggests GLP-1 drugs may actually have protective urinary effects in certain contexts

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Patients with insulin resistance, hypothyroidism, or PCOS may see slower initial results

This was done by changing out a few of the amino acids making it more difficult for the body to degrade