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And, as contemporary science continues to validate its key mechanisms, it will continue to help well-trained individuals achieve real physique and performance improvements for years to come

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Reimbursement and formulary status for GLP-1 RAs depend on: clinical endpoints (A1c and weight loss thresholds), tolerability and discontinuation rates, and increasingly, cardiometabolic outcomes

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Unlike type 2 diabetes mellitus, for which many drug choices are available, the only available therapy for type 1 diabetes is insulin (Sodium Glucose cotransporters inhibitors are used as adjuvant therapy for uncontrolled T1DM and a body mass index (BMI) of 27 kg/m 2 )

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