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Since melanocytes and Schwann cells can originate from SCPs, such associations usually complicates the diagnosis of these tumours, expressing both melanocytic and Schwann cell markers

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doi: 10.1089/105072501300176462 28 Rodriguez-DiazEPearceEN

EPN-1::GFP is readily visualized in all four blastomeres at the four-cell stage of embryogenesis, and RNAi efficiently reduces EPN-1::GFP to undetectable levels at the 4-cell stage (Figure 1B, left)

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More importantly, Kla preferably affects enzymes involved in metabolic pathways, including glucose metabolism, TCA cycle, amino acid metabolism, fatty acid metabolism, and nucleotide metabolism, and that elevated Kla levels on metastasis-related substrate are strongly correlated with aggressive clinical features and driver mutations of HCC