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Each run was conducted with one mouse from each treatment group and with run-to-run alternation so that treatments were equally distributed across all four arenas

They are different molecules with different receptor binding affinities

Musso G, Cassader M, Paschetta E, Gambino R (2017) Thiazolidinediones and advanced liver fibrosis in nonalcoholic steatohepatitis: a meta-analysis

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However, people can still catch the virus outside the typical flu season