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For everyone else, the overall safety record in humans has been very reassuring
[1] [7] Additionally, because glucagon promotes glycogenolysis and gluconeogenesis, there is a theoretical concern regarding glucose management in people with type 2 diabetes, although the GLP-1 and GIP components appear to counterbalance this effect in practice
This equilibration step prevents condensation formation that can lead to peptide hydrolysis or aggregation
Precaution should be taken in people with acute pancreatitis, gallbladder disease, hypoglycemia, acute kidney problems, diabetic retinopathy, rapid heartbeat, and suicidal behavior or thoughts
other diabetes medications had between a 32% to 68% lower risk of opioid overdose, compared to other treatments
