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4 Device architecture and conceptualization A well-defined OoC architecture is essential for faithfully mimicking the structural and functional features of native tissues

Background and aims: cell dedifferentiation is recognized as one of the mechanisms responsible for the disappearance of cells from pancreatic islets of diabetic subjects, but the underlying process is still unclear

Some studies suggest that taking ornithine prior to consuming alcohol may reduce hangovers due to alcohol increasing ammonia levels

Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term culture

Milder cases typically require fewer treatments per week

Conversely, we observed a significant increase in 18:3-bearing cholesterol esters and vinyl ether-linked phosphatidylcholine and phosphatidylethanolamine in ESA-treated ACSL1 -deficient cells