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These findings indicate that the integration of the modified Zhengan Xifeng Decoction with cobamamide may offer superior therapeutic benefits in tinnitus associated with hyperactivity of the liver yang by targeting both symptomatic relief and underlying biological mechanisms

Laskovs, M., Partridge, L

doi: 10.3390/ijms25041972 5 AlmomaniBAElayyanRNAl-ShatnawiSF

Nrf2 is a transcription factor that upregulates antioxidant enzymes (e.g., glutathione S-transferases, GSTs) and phase II detoxification enzymes (e.g., UDP-glucuronosyltransferases, UGTs) (137)