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The initial consultation involves a thorough history, including length of GLP-1 RA treatment, estimated weight loss, future treatment plans, history of cosmetic procedures, comorbidities, and medication reconciliation

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This is particularly interesting as next-generation multi-receptor agonists that incorporate glucagon receptor agonism have shown tremendous promise for weight loss and glycemic control, including triagonists for the GLP-1R, GIPR and GCGR 44,45

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This includes dietary inputs, microbial balance, and targeted interventions that support long-term signaling stability