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Gallup found that the use of these drugs specifically to lose weight (theyre also used to treat diabetes) has more than doubled from February 2024, when it was 5.8%, to 12.4% currently: More women (15.2%) are taking the drugs than men (9.7%), which correlates with a slightly larger decline in obesity rates among women

They act on the hypothalamus, the brain's hunger center, boosting fullness signals and dialing down hunger

Gastrointestinal tolerability is another significant factor

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2)

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