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In Phase 2 clinical trials, retatrutide was administered as a once-weekly subcutaneous injection , following a structured dose escalation protocol designed to minimise gastrointestinal side effects whilst optimising efficacy

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While regulatory streamlining is occurring, it may not fully offset these systemic issues

Patients should not change doses or skip instructions on their own

Catch up on demand across three sessions and hear how AF management is changing Link in comments The first session on 'Breaking Barriers in Persistent AF: Delivering Results That Last' highlights what matters most for long-term success by exploring the latest data, including insights from the ADVANTAGE study Dr Andreas Metzner and Dr Joaquin Osca Asensi also guide a live case, showing how experts in leading centres apply these findings to refine their practice and provide real-world insight