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Limited scope each peptide typically affects one or two pathways

Consistent with this hypothesis, interrogation of our gene expression microarray data sets revealed increased expression of several JNK regulatory genes including the toxicity and JNK inducer TAJ ( TNFRSF19 , 8.33-fold, adjusted P -value 1.25 10 18 , Supplementary Table 1), and JNK target genes including the p53-inducible proteins TP53I3 ( PIG3 , 5.02-fold, adjusted P -value 1.73 10 16 ) and CDKN1A ( p21 , 4.87-fold, adjusted P -value 9.62 10 15 ) in GSTP1 knockdown cells

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

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Oxidative DNA damage and antioxidant defense after reperfusion in acute myocardial infarction

Real-world evidence on the utilization, clinical and comparative effectiveness, and adverse effects of newer GLP-1RA-based weight-loss therapies