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[1] Although water-soluble vitamins are generally excreted through urine when consumed in excess, vitamin B12 is unique in that significant amounts are stored in the liver

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It could also be due to the adipocyte dysfunction linked to low vitamin B12 levels through cellular inflammation

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AOD9604 and Heart Disease Though fat reduction and weight loss directly reduce the risk of heart disease, there is evidence to suggest that AOD9604 has beneficial effects on the heart beyond its ability to reduce fat burden