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Structural and functional evolution of positively selected sites in pine glutathione S-transferase enzyme family

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1 Introduction Gout is a metabolic rheumatic disease caused by abnormalities in purine metabolism or reduced uric acid excretion, with hyperuricemia as the central pathological feature

doi: 10.1089/ars.2013.5605

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We found a significant downregulation of CXCR4, CXCR1, CXCR2, CCR2 receptors on HUVEC cells exposed to cell products/CMs from all the PCa and BPH cell lines (Fig