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doi: 10.3390/ijms22126223 75 JayantiS.MorettiR.TiribelliC.GazzinS

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2.2.5 Metabolic reprogramming Metabolic reprogramming refers to the process in which cells, under specific physiological and pathological conditions, systematically adjust and transform their metabolic patterns to adapt to changes in the external environment and to meet their own needs for growth and differentiation, by engaging various bioenergetic routes, such as glucose utilization, lipid metabolism, and amino acid metabolism (Xia et al., 2021