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Micevic G, Muthusamy V, Damsky W, Theodosakis N, Liu X, Meeth K et al

Key Takeaway: While standard antihistamines are usually fine, combination D products containing pseudoephedrine require extra caution due to their potential impact on blood sugar and heart rate

The structural change ( Figure 7E ) could potentially hinder the transamination reaction, because the loop movement might bring the -amino group of PMP into closer proximity to other amino-acid side groups, such as His192, promoting the hydrogen bond formation that may influence the reactivity of PMP with GSA

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