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Moreover, besides binding of minor fraction of Cu(II) ions, His can also act as a catalyst enhancing the rate of the copper transfer between CuHSA and other proteins and cellular destinations, which might be the most important physiological role of His in copper metabolism

For instance, insufficiency of several dietary components increases the risk of developing stroke, a pathological condition that results from impaired cerebral blood supply

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When oxidative stress interferes with those cycles, your body cant fully reset

These results show much clinical promise, as the magnitude of improvement in patients is comparable to the standard of care, acetazolamide

Enzulatamide (Xtandi Capsules) [online], (2012)