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The compound was also investigated as PL14736 in early-phase IBD clinical work, as described in a 2008 paper by Klicek and colleagues in Journal of Pharmacological Sciences , though that clinical program was never completed or approved

DSIP has been discussed as a pharmacological intervention to fight fatigue and sleep loss in military interventions

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A leaky gut allows harmful substances to pass into the bloodstream, which triggers chronic inflammation, leading to more histamine release and poor breakdown