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IGF-1 combats the loss of muscle mass in old age, both by promoting new tissue growth and retarding apoptosis (cell suicide that protects against infection and cancer, but that can kill healthy cells as we get older)

Study population A total of 120 participants with a diagnosis of type 2 diabetes and HbA 1c 48 mmol/mol (6.5%) were included in the SEMPA trial

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations