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Key results (52 weeks): Max walking distance 13% (median gain: +26 m) Pain-free walking distance 11% (median gain: +14 m) QoL (VascuQoL-6) improved significantly Lower rates of rescue treatment and (HR 0.46) Effects persisted 5 weeks after treatment stopped Better anklebrachial index, HbA1c, and weight loss (5.2 kg) Safety: Well tolerated Serious adverse events similar to placebo (19% vs 20%) Discontinuation due to AEs: 7% (semaglutide) vs 4% (placebo) No treatment-related deaths How does it compare

R.NonakaT.HasegawaM.et al

Legal Status / FDA GHRP-6 is not FDA-approved for any human medical indication

doi: 10.2337/db19-1004-P 46 MosenzonO.WiviottS

Findings from a national study in the Czech Republic evaluating use of GLP-1s after nonfatal MI or stroke in patients with diabetes were published in the European Journal of Preventive Cardiology

Once reconstituted, store in the refrigerator