Food and Drug Administration (FDA): Ozempic, Rybelsus, and Wegovy
Although both are analogs of human GLP-1, there are a few molecular differences between these two agents that may be the reason that a hypersensitivity reaction occurred with liraglutide and not semaglutide
Proven Efficacy: Achieves up to 17% weight loss in patients with full treatment adherence, matching the established clinical outcomes of weekly injections
Aspiration Risk: Like other GLP-1s, semaglutide may increase the risk of aspiration during anesthesia
Injection Site Reactions As with any injectable medication, there may be minor irritation or reactions at the injection site
Suicidal ideations - Bupropion can worsen suicidal thoughts in patients who have them, especially in children, adolescents, and young adults