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No current research doesn't support a permanent change in skin colour

Adipose tissue macrophage-derived exosomes induce ferroptosis via glutathione synthesis inhibition by targeting SLC7A11 in obesity-induced cardiac injury

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These data do not indicate if transcript suppression was a direct result of AG-120 treatment or rather a second level consequence of mitochondrial injury, the known mechanism of AG-120 suggests the latter explanation is more likely