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Collectively, systematic nutritional intervention is expected to become the third major treatment alongside physical and drug therapy, enabling more OA patients to avoid adverse effects caused by repeated drug use and potential risks associated with surgery and prosthesis replacement

The dosage and frequency depend on the severity of the deficiency and the underlying cause

Eat balanced diets rich in antioxidants to ensure that your body has ample glutathione

BoschmannMSteinigerJHilleUTankJAdamsFSharmaAMet al

2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration