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It is generally avoided in pregnancy, in people with certain gastrointestinal conditions, and where a clinician identifies a contraindication during screening

Several nutritional and lifestyle factors are associated with better testosterone status

By restoring physiological insulin flux, MI lowers the oxidative burden and restores redox-sensitive transcriptional control (169)

Resistance training and higher dietary protein intake are strongly recommended to counteract sarcopenic effects

Therefore, larger-scale clinical trials are needed to validate these results and confirm the utility of proline supplementation in a clinical ART setting

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