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Wadden and colleagues thereby conducted a research titled Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial and the summary has been given below

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Semaglutide reaches peak levels in the body about 13 days after injection

Nighttime snacking increases ghrelin (hunger hormone) and decreases leptin (fullness hormone) that can lead to increased cravings for high-calorie comfort foods

With semaglutide, the most frequent errors include starting at too high a dose, rushing through the titration schedule, improper reconstitution, and poor storage